This is a nice shot.
These are not criticisms they are just ways that you could change this kind of shot in the future.
If may have been better if you had panned a bit left, to get the Shard on the left 1/3 of the image. Also it would have been nice to see more of the bridge on the left, but this bit of the shot is often blocked.
You could have cleaned your lens before hand which would have helped with all the large white blobs in the sky.
If you had shot earlier in the evening you would have got more life in the sky and it would have reduced the glare from the bridge street lighting.
You could also have corrected the verticals to give it a more classic architectural look.
Hope that helps.