I have, last week in fact, replaced a 250 with a 150.
The 250 I found gave too greater magnification for general use.
Also the working distance was very short, about 3"-4" on my 55-200 if I recall.
Whereas the 150 if find gives a more useful magnification for flowers, insects and similar stuff.
The working distance has gone out to 8"-9" depending on which end of the zoom I'm using.
Focusing with the 150 I also find much easier, less magnification, greater DOF.
With lens on manual moving the camera back and forth untill focus is achieved.
The 'shots' below, of a £2 coin, are just to show the 'magnification' available at each end of my 55-200 zoom.
They were very quick shots and
no particular attention was paid to focusing or exposure.
D in W
200mm
DSC_0014-RS by
Dave in Wales, on Flickr
55mm
DSC_0017-RS by
Dave in Wales, on Flickr