You know i thought about this-it has been said many times when shooting in raw the in camera sharpening will not take effect. So why would any enhancements in colour saturation either-especially on nikon as these are incorporated in the same setting.
Maybe its different on canon
It doesnt make any difference what settings like that you use in camera if you are using RAW........they only affect jpg.
On my Canon I leave it in Neutral setting, easier to fiddle about with in PS afterwards