Sorry guys, I've not been on the forum for a bit due to travelling........yes I have the 400 DO mk2 and the mk3 1.4 and 2x.
The 1.4 is permanently connected to the 400 (obviously giving me 560mm f5.6) and I'd say the performance in terms of the AF (with a 1Dx mk2) is virtually indistinguishable from the prime lens, everything works extremely well, full af point selection etc and IQ excellent.
Using the 2x does give a slight drop in performance (esp if you pixel peep!!) and a slowdown in af, but is still perfectly useable for the majority of cases and again gives full af point selection.
I did have the mk2 TCs originally but upgraded to the mk3 as soon as they came out, and IMO the upgrade is really worth doing for most lenses but especially with the mk2 (and mk3) super teles.
BTW the 1.4 works well with the mk 2 100-400 as well, giving a useful and light 560mm.
George.