On my 50D the half pressed shutter sets the AF only, not the exposure meter. Therefore the exposure settings will change as I move the camera around a contrasty scene when I have the shutter button half depressed, whilst the AFstays locked. I have not altered any of the camera's AF settings out of the box to make this happen. I can see the AF-ON button's usefulness for tracking moving subjects, as you don't have to refocus every time you lift your finger from the shutter button. But if I want to use exposure lock when re-composing a picture it's kind of tricky to use the * (AE lock) button and the AF-ON at the same time, so, in that situation I will use a half-depressed shutter button for focussing and the * button for metering in conjunction.