The Weddings Police will be along shortly to chop your balls off, so I'll leave you to them
Manual exposure control is a bit of a misnomer IMHO. We all use different modes and methods to get the result we want, often with some degree of 'manual' intervention. The big difference with Manual is that once you've set it, it will not change. You can use Manual just fine, with flash set on E-TTL auto, and it will try and balance the flash with the f/number you've set.
No different to Av in that respect, but in Av the camera will shift the shutter speed to maintain correct ambient exposure without you having to worry about it. That's just the way I like to work, and I trust the camera (with evaluative metering) to get at least pretty close to what I want, and then I tweak it with compensation as necessary. TBH, I sometimes tweak the flash exposure quite a lot, not so much because the camera has got it 'wrong' but with fill flash I like the result to be more subtle than obvious, so I turn it down a bit.
If you use Av, make sure the camera is set to give correct ambient exposure - on my 40D, Custom Function 1-7 should be set to auto - otherwise it will stay locked on the x-sync speed (is that 1/200sec with a 450D?) whenever the flash is switched on.
Get to know your flash unit. They are very clever devices these days and can seem a bit complicated and confusing. A few sessions with the instruction book, interspersed with some practice picture taking to see what it actually does, will get you sorted. Basically with Canon (unlike Nikon) the gun controls the flash independently, and the camera sets the ambient bit, then the two are nicely integrated in the camera's metering system that can distinguish between the two.
I'm not sure that you want to get involved with the High Speed flash sync mode just yet, or second curtain slow-sync technique (dragging the shutter), but you might like to try and balance the flash and ambient white balance if you're shooting indoors under tungsten light.
StoFen sell a yellow-orange version to do this, but I stuff mine with the cellophane wrapper from a box of Quality Street (it might have been Roses

). Does the same thing and I switch the camera to Tungsten white balance and it comes out a treat. This might sound a bit crude, but since every form of artificial light varies in colour temperature, it's impossible to get an exact match, so be sure to shoot Raw and tweak it in post processing.
Oh and just another tip, since you will get your balls chopped off again if you make the bride's dress green, try to get at least one reference pic with a grey card against the bride's dress. Inside of a Lowepro bag is 18% grey, and I'm going to get me a handy 18% grey lens cloth like this
http://www.warehouseexpress.com/buy-spudz-10x10-18-grey/p1013798