Sigma 300mm f2.8 or Canon 300Mm f4 IS

While it depends on what your shooting and where I would always plump for the 300 f/4 IS. Much smaller and easier to transport. It is slower by a stop but you gain two-four stops with the IS (depending on what you are shooting as to whether IS is actually useful). The big plus however is the size IMO.

I used to have the Non IS version of the 300 f/4 and it was beautiful.
 
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