Well, I have never seen tower bridge taken from this angle.
I quite like it.
I would however suggest a clockwise rotation to make it level.
The exposure is perfect as is the sharpening etc.
I like the strong colours you've used and saturation applied, but reckin if its level it will be better.
Sadly the railing lets it down, I bet without it, your shot would be nicer again...get cloning out...