I would say heed CT's advice and approach micro adjustment with some caution. It really
shouldn't be necessary, though I guess sometimes it is.
My experience is, know exactly what you're doing, do
not make adjustments at an artificially close distance (it will probably throw everything out at normal range), bear in mind that the whole system is subject to variable tolerances according to zoom focal length and focus distance, and that the adjustments made are very fine indeed relative to actual general use.
Since getting micro adjust on my 5D2, I have checked all my lenses till my eyes bled (as you do

) and my conclusion is a) it's really not necessary, and b) the 5D2's AF system is incredibly accurate and very consistent - like within a
few mms in ten feet, bang on every time!
Most of the time, you just can't target the focus that accurately in practise, there is no need to anyway, and depth of field more than covers any small discrepencies.
Here's what Canon's Chuck Westfall has to say on doing it - second post down
http://www.digitaljournalist.org/issue0812/tech-tips.html