Hi David
Vertical.....#1 for me but with a boost of saturation...I like the way my eye is drawn up the height ladder (just a small patch top right to clone out )
Mouth...not the easiest of subjects without doing the obvious ( which I did
) so I quite like this fun take & your plain background is a great start
.....you mention it looking a bit soft in places ? I don't fully understand focus points myself but from what I can see you may have focused on the rear arm, leg & the little doll's foot & as you shot at f4.5 depth of field is really slim meaning the front of the image is out of focus . If I remember correctly ( for landscapes anyway) you focus ideally about 1/3 of the way in to the image ,this then gives the rear 2/3rd's in focus & the front 1/3rd in focus.................at least I think that's the theory !
If you feel like trying again , I'd suggest something like f8-f11 , stick it on a tripod , focus maybe somewhere like the middle of the foremost arm, camera self timer on & see what result that gives you. Turn the VR/IS off when using the tripod.
& if all the above is teaching my granny to suck egg's please feel free to ignore me & I apologise