Plenty of places to stay depending on your budget.
On the south you are better looking near the airport, plenty of cheap places for a one or two night stay. Then there are shuttle buses to an Interchange at Liverpool South Parkway where you can catch a train every 15mins into the centre. Leave your car at the hotel - the trains and buses work well.
You could train it into Lime Street, and again there are plenty of Premier Inn/Travelodge type places within easy reach. If you want me to go and do a recce just holler - my bus pass gives me free travel on the trains. (Your pass only works on the buses - if you are old enough to have one!) My choice would be to train it all the way and leave the car at home.
I've just entered Liverpool into Booking.com and it comes up with a multitude of decent places in Central Liverpool. Don't rule out staying on the Waterfront - Albert Dock area. Good hotels and good eating places, plus great night time photo opportunities.
When are you thinking of coming? I'm happy to guide you round the place. Photo opportunities are more than you can fit into a weekend so you won't go short.
@Mr Perceptive will find it hard to keep away.
PM me for pnone numbers if you want a natter.
Edit....No problem if Mrs comes along. There's Liverpool One, which is a town centre out of town shopping Mall. Plus a ginormous John Lewis. All she will need is your credit card!