Having had it on trial and with the current discount, I decided to purchase Denoise AI.
I don't have very many noisy images, but the first one I tried it on cleaned up a treat.
I did however find it rather slow so I think it's something to use when justified, and yes - I do have a pretty advanced graphics card.
I also use Topaz "Studio2" which has a tool called "AI Clear" which is a sort of combined noise reduction plus sharpening tool which I find very useful on a lot of images, although the NR is not as powerful as Denoise AI.
I was watching a Topaz webinar a while ago and the presenter (whose name I've forgotten) said he uses AI Clear on ALL his images, although the webinar was being promoted by Topaz.
I find it useful on many of my images, when I remember to use it.